It's best to take prednisone as a single dose once a day straight after breakfast. For example if your dose is 30mg daily, it's usual to take 6 tablets (6 x 5mg) all at the same time after breakfast. The most common 5-day prednisone dosage follows a tapering schedule, starting with a higher dose (like 40-60mg) on the first day and gradually decreasing over the five days to minimize side effects while maximizing benefits. Find out what constitutes a high dose of prednisone, how it can be used to treat inflammation-related conditions, and ways to ensure you take it safely. Medscape - Anti-inflammatory-specific dosing for Prednisone Intensol (prednisone), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation. The prednisone dosing tool provides starting dose, taper schedule, and corticosteroid conversions. Whether you're treating asthma, autoimmune conditions, or inflammation, this steroid taper calculator helps you plan your medication safely. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. Prednisone can be prescribed at any dose and the 50 mg prednisone tablet dose is the least commonly prescribed. If your doctor prescribes prednisone 50 for 5 days, either the 50 mg tablet or an equivalent dose using other strengths may be used. Detailed Prednisone dosage information for adults and children. Includes dosages for Osteoarthritis, Asthma - Maintenance, Rheumatoid Arthritis and more; plus renal, liver and dialysis adjustments. Prednisone dosages can range from 5 mg to 60 mg a day. Find out more in this guide to prednisone dosages for adults and children. The initial dosage of prednisone may vary from 5 mg to 60 mg per day, depending on the specific disease entity being treated. In situations of less severity lower doses will generally suffice, while in selected patients higher initial doses may be required.